Like airport security barriers that either clear authorized or block unauthorized travelers and their luggage from accessing central operation areas, the blood-brain barrier (BBB) tightly controls the transport of essential nutrients and energy metabolites into the brain and staves off unwanted substances circulating in the blood stream.
Source: Enhanced human Blood-Brain Barrier Chip performs in vivo-like drug and antibody transport
New “Organ on a Chip” technology is being developed. When it is available after the necessary years of testing it may help people with meningitis, hydrocephalus, and other severe spine- and brain-related problems from other diseases as well as from Valley Fever symptoms. Although there are antifungal drugs for Valley Fever that cross the blood-brain barrier now, perhaps this experimental technology will allow the doses to be lowered so the toxic side effects will not be as severe.